… The bivalent compound 8 containing guanidine was synthesized with FTI-276, and biological
evaluation showed that the methyl ester form compound 8b could inhibit the formation of …

… into researcher attention another potential anticancer mechanism, that is, inhibition of
enzymes with a key role in tumor cell proliferation, such as farnesyltransferase [26,29,30,31]. …

… Starting from these premises, our group designed PEGylated phenothiazine derivatives
as new building blocks for anticancer drugs. PEG has been bonded to the phenothiazine …

… The review included the extract of the studies in the past twenty years that were
performed globally, specifically on the synthesis and biological assessment of N-acylphenothiazines. …

Theoretical and experimental data concerning the versatile approaches for the synthesis of
N-acylphenothiazines were systematized in this review. The aim of this research was to …

… 5) 12a as an FTase inhibitor at the micromolar range. The same research group synthesized
a series of phenothiazine-1,2,3-triazole hybrids as FTase inhibitors (FTIs) with potential anti…

… phenothiazine containing … phenothiazine containing an ester unit (coded PPO) was prepared
by an esterification reaction of the phenothiazine acetic acid intermediate. Their synthesis …